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. 2020 Nov 9;10:19340. doi: 10.1038/s41598-020-75051-3

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Borrelia and Babesia peptides. (A) Borrelia peptides (160) identified in patients affected by acute Lyme borreliosis, post treatment Lyme disease syndrome or suspected of tick-borne illnesses. Proteins marked with a * were unambiguously (100% sequence identity with the pathogen with less than 90% homology with human and other organisms) attributed to the following species: Borrelia hermsii, Borrelia turicatae, Borrelia duttonii, Borrelia miyamotoi, Borrelia recurrentis. Unmarked proteins were attributed to the following species: Borrelia burgdorferi, Borrelia mayonii, Borrelia garinii, Borrelia afzelii, Borrelia bavariensis, Borrelia spielmani. (B) Babesia peptides (n = 62) identified in patients diagnosed with post treatment Lyme disease syndrome. 37/148 non acute patients had at least one Babesia urinary peptide, and 17/148 non acute patients had two or more peptides. This figure was prepared using CorelDRAW X7.