Table 1.
Demographic information of patients enrolled in this study.
| Characteristics | Patients | Controls | |||
|---|---|---|---|---|---|
| Acute LB | PTLDS | NA-TBI | Diseased controls | Healthy controls | |
| N | 10 | 36 | 112 | 215 | 35 |
| Age (median) | 52.5 (IQR = 14) | 50 (IQR = 25) | 46 (IQR = 32) | 35.5 (IQR = 31) | 31 (IQR = 60) |
| Sex | |||||
| Male/female | 4/6 | 14/22 | 54/58 | 112/57 | 18/17 |
| NA | – | – | – | 46 | – |
| Tick discovered | 6Y/ N | 11Y/10N | 11Y/15N | – | – |
| Erythema migrans rash | 10Y/0N | 26Y/5Na | 24Na | – | – |
| Muscoskeletal pain | 7Y/0N | 22Y/4N | 15Y/N | – | – |
| Fatigue | 7Y/0N | 18Y/6N | 20Y/4N | – | – |
| Fever | 7Y/0N | 11Y/13a | 7Y/17Na | ||
| Facial palsy | 1Y/3N | 3Y/20Na | 3Y/21Na | – | – |
| Cognitive impairment | 4Y/0N | 16Y/7N | 9Y/14N | – | – |
| Serology (Pos) | 10Y/0Nb | 19Y/4N | 12Y/14N | ||
Demographic and clinical characteristics of sample cohort.
Acute LB acute Lyme Borreliosis, PTLDS post treatment Lyme disease syndrome, NA-TBI suspected non-acute tick borne infection.
aA history of Erythema migrans, fever, and facial palsy were recorded for PTLDS and TBI patients.
bThe urine was collected before treatment regimen for all patients. All 10 acute patients were verified to be two tier serology positive 3–6 weeks later.