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. 2020 Nov 9;10:19340. doi: 10.1038/s41598-020-75051-3

Table 2.

Borrelia peptides identified in the urine of acute Lyme borreliosis cases.

Sample ID EM rash Acute LB symptoms Serology Under treatment (at time of collection) Number of identified Borrelia peptides Peptide sequence
108838 Y Y Pos No 3 IDTEEAAVK; NAGNFEIIR; VTLSDISTK
104821 Y Y Pos No 2 AILKTNGDKTLGAAELEK; NNFCLSKSDLEEIR
790907 Y Y Pos No 2 SNQDNQTLLLSLHQAIAK; LKNSHAELGVAGNGATTDENAQK
889597 Y Y Pos Yes (2 days doxycicline) 2 GGYLDHVNHAGAKKVILTVPAK LATVNEAEGK
213567 Y Y Pos No 2 LATVNEAEGK; NDVSEEKPEIK
453742 Ya Ya Pos No 3 VVILNEATGK; LATVNEAEGK; FVYIGNVDNMGYTINFK;
463256 Y N Pos No 2 NLSLFTDFYEISMMNAYFIK; QKATGAINAVSGEQIL
459235 Y Y Pos Yes (1 day doxycicline) 2 SAKEVINNTSTMEK; SSSVDGFVSFKEYKER
729340 Y Y Pos No 1 FEDAIVLRDK
310741 Y Y Pos No 2 VNESDLGIKALDEK; FNVEACFPTLIVEK

The urine was collected before treatment regimen for all patients. All 10 acute patients were verified to be two tier serology positive 3–6 weeks later. Acute Lyme Borreliosis symptoms = joint pain, fatigue, facial palsy, neurological symptoms.

aDeveloped after collection.