. 2020 Nov 9;10:19327. doi: 10.1038/s41598-020-76232-w

Table 3.

Sensitivity and specificity of genotype predictions of resistant antimicrobial phenotype for E. coli isolates by time point and treatment group for tetA and tetB genes. 1. Time point in days when sample was collected; 2. Treatment group; 3. Number of isolates from each treatment group for each sampling time point; 4. Number of isolates for which both the referred antimicrobial resistance gene and corresponding resistance phenotype were observed; 5. Number of isolates for which the referred antimicrobial resistance gene was not detected, but the expected corresponding resistance phenotype were observed; 6. Number of isolates for which the referred antimicrobial resistance gene was detected, but the expected corresponding resistance phenotype was not observed; 7. Number of isolates for which both the referred antimicrobial resistance gene and corresponding resistance phenotype were not observed; 8. Sensitivity for the referred resistance gene to correctly predict phenotypic resistance to the corresponding antimicrobial drug; 9. Specificity for the absence of the referred resistance gene and prediction of lack of phenotypic resistance to the corresponding antimicrobial drug.

Time point¹	Tx group²	N° isolates³	tetA						tetB
Time point¹	Tx group²	N° isolates³	G+: P+⁴	G−: P+⁵	G+: P−⁶	G−: P−⁷	Se⁸	Sp⁹	G+: P+⁴	G−: P+⁵	G+: P−⁶	G−: P−⁷	Se⁸	Sp⁹
0	CTL	21	14	5	0	2	73.7	100	15	4	0	2	78.9	100
	ENR	22	11	4	1	6	73.3	85.7	10	5	0	7	66.7	100
	TUL	24	21	2	0	1	91.3	100	17	6	0	1	73.9	100
7	CTL	21	15	1	0	5	93.8	100	10	6	0	5	62.5	100
	ENR	22	19	2	0	1	90.5	100	16	5	0	1	76.2	100
	TUL	24	18	3	0	3	85.7	100	14	7	0	3	66.7	100
28	CTL	21	5	7	0	9	50.0	100	6	6	0	9	50.0	100
	ENR	22	12	2	1	8	57.1	100	8	6	0	8	57.1	100
	TUL	24	12	2	0	10	28.6	100	4	10	0	10	28.6	100
56	CTL	20	4	1	1	14	80.0	93.3	1	4	0	15	20.0	100
	ENR	20	2	0	2	16	100.0	88.9	0	2	0	18	0.0	100
	TUL	23	4	0	0	19	100.0	100	0	4	0	19	0.0	100