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. 2020 Nov 6;25:e925229-1–e925229-9. doi: 10.12659/AOT.925229

Table 4.

Cox proportional hazards model analysis of biopsy-proven acute rejection.

Univariate Multivariable
Hazard ratio 95% CI P value Hazard ratio 95% CI P value
Group
 Offspring to mother 1 0.843 1 0.910
 Husband to wife 1.22 0.62 2.40 0.560 0.94 0.41 2.17 0.880
 Other unrelated 1.09 0.42 2.78 0.863 0.97 0.34 2.75 0.955
Age 0.99 0.96 1.03 0.727
BMI 1.05 0.96 1.15 0.308
Number of HLA mismatch (ABDR) 1.16 0.92 1.45 0.210
Number of HLA mismatch (DR) 1.44 0.83 2.48 0.195 1.48 0.73 2.85 0.286
Pre-transplant DSA 3.07 1.52 6.20 0.002 2.10 1.06 4.15 0.034
ABO-incompatibility 1.27 0.63 2.54 0.501
Cold ischemic time 1.01 1.00 1.02 0.276
Donor age 1.00 0.97 1.03 0.951
Donor creatinine 0.80 0.08 8.24 0.850

BMI – body mass index; HLA – human leukocyte antigen; DSA – donor-specific antibody; CI – confidence interval.