Table 2.
Correlation analysis between ZBTB7A and related markers of immune cells
| Description | Gene marker | ZBTB7A (Purity) | |
|---|---|---|---|
| Cor | P | ||
| CD8+ T cell | CD8A | 0.175 | ** |
| CD8B | 0.105 | 0.074 | |
| T cell (general) | CD3D | 0.139 | ** |
| CD3E | 0.215 | *** | |
| CD2 | 0.167 | ** | |
| B cell | CD79A | 0.121 | * |
| CD19 | 0.042 | 0.471 | |
| TAM | CD68 | 0.22 | *** |
| CCL2 | – 0.05 | 0.395 | |
| IL10 | – 0.004 | 0.945 | |
| Neutrophils | CD66b (CEACAM8) | 0.309 | *** |
| CD11b (ITGAM) | 0.294 | *** | |
| CCR7 | 0.222 | *** | |
| Dendritic cell | HLA-DPB1 | 0.212 | *** |
| HLA-DQB1 | 0.134 | * | |
| HLA-DRA | 0.255 | *** | |
| HLA-DPA1 | 0.238 | *** | |
| BDCA1 (CD1c) | 0.246 | *** | |
| BDCA4 (NRP1) | 0.226 | *** | |
| CD11c (ITGAX) | 0.259 | *** | |
| Th1 | STAT4 | 0.166 | ** |
| T-bet (TBX21) | 0.154 | ** | |
| CD4 | 0.195 | *** | |
| TNF-α (TNF) | 0.041 | 0.484 | |
| IFN-γ (IFNG) | 0.083 | 0.159 | |
| Th2 | GATA3 | 0.135 | * |
| STAT6 | 0.328 | *** | |
| STAT5A | 0.273 | *** | |
| CCR4 | 0.333 | *** | |
| IL13 | 0.066 | 0.259 | |
| CXCR4 | – 0.039 | 0.508 | |
| Th17 | STAT3 | 0.459 | *** |
| IL17A | 0.059 | 0.317 | |
| Treg | TGFβ (TGFB1) | 0.194 | *** |
| STAT5B | 0.336 | *** | |
| CCR8 | 0.279 | *** | |
TAM, tumor-associated macrophage; Th: T helper cell; Treg, regulatory T cell; Cor, R value of Spearman’s correlation; Purity, correlation adjusted by purity. *P < 0.05, **P < 0.01, ***P < 0.001