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Curcumin attenuated the podocyte loss and apoptosis in PHN rats. (a) Podocyte number in the glomerular was estimated with the immunohistochemistry (scale bars 20 μm, designated by the percentage of positive areas in glomerulus). (b) Expression of Bcl-2, Bax, and Caspase-3, the apoptosis-related proteins in renal tissues. ∗P < 0.05; ∗∗P < 0.01, the model group vs. the control group, ▲P < 0.05; ▲▲P < 0.01, the model group vs. the curcumin (300 mg/kg) group.
