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. 2020 Nov 1;2020:7069052. doi: 10.1155/2020/7069052

Figure 3.

Figure 3

Curcumin treatment improves the autophagy of podocyte in PHN rats. (a) Representative western blotting images of beclin1, LC3 II, and LC3 I in the renal tissues of PHN rats. GAPDH is used as a loading control. (b) Quantification of beclin1 in the PHN rats. (c) Quantification of the LC3 II/LC3 I ratio in the PHN rats. (d) The ultrastructure of autophagosomes (arrows) of podocytes in the control and model groups was detected by the transmission electron microscopy (TEM, original magnification ×6000). (e) Immunofluorescence staining for p62 expression in the renal tissues of PHN rats (scale bars 20 μm). (f) Analysis of fluorescence intensity of p62-positive cells in the PHN rats. ∗∗P < 0.01, the model group vs. the control group, ▲P < 0.05 the model group vs. the curcumin (300 mg/kg) group.