Table 1.
Demographic and clinical characteristics of observed patients.
| All patients(n=21) | |
|---|---|
| Age (years), median (IQR) | 60 [57–64] (48–74) |
| Male gender, n (total) | 18 (21) |
| BMI (kg/m²), median (IQR) | 30 [27–32] (21–42) |
| Caucasian ethnicity, n (total) | 18 (21) |
| Obesity (BMI ≥30 kg/m²), n (total) | 11 (21) |
| Hypertension, n (total) | 11 (21) |
| COPD, n (total) | 4 (21) |
| Asthma, n (total) | 3 (21) |
| CAD, n (total) | 3 (21) |
| On arrival at the ICU | |
| APACHE II, median (IQR) | 14 [12–20] (9–22) |
| SOFA score, median (IQR) | 6 [4–8] (3–12) |
| Time-interval between symptoms onset and ICU admission, median (IQR) | 9 [8–11] (4–15) |
| PAFI, median (IQR) | 91 [67–135] (44–260) |
| During ICU stay | |
| ICU stay duration, median (IQR) | 15 (7–26) (5–28) |
| Patients having received UFHa, n (total) | 13 (21) |
| UFH daily dose (IU/kg/day), median (IQR) | 441 [338–587] (0–800) |
| Patients having received LMWHa, n (total) | 19 (21) |
| LMWH daily dose (IU/kg/day), median (IQR) | 100 [53–149] (0–230) |
| Non-invasive ventilation, n (tot) | 3 (21) |
| Invasive ventilation support, n (tot) | 19 (21) |
| ECMO, n (tot) | 5 (21) |
| Vasopressor use, n (tot) | 16 (21) |
| New renal replacement therapy, n (tot) | 6 (21) |
| Thrombotic complicationsb | 10 (21) |
| Major bleeding according to the ISTHb | 6 (21) |
| Death, n (tot) | 3 (21) |
| Discharged from ICU at the end of observation period, n (tot) | 9 (21) |
a
Patients may have received UFH or LMWH at different periods of ICU stay.
b
See the companion paper for the descriptions of the events.
IQR, interquartile range; BMI, body mass index; COPD, chronic obstructive pulmonary disease; CAD, coronary artery disease; ICU, intensive care unit; IQR, interquartile range; APACHE II score, acute physiology and chronic health disease classification system II; SOFA, sepsis-related organ failure assessment; PAFI, PaO2/FiO2 ratio; UFH, unfractionated heparin; LWMH, low molecular weight heparin; ECMO, extracorporeal membrane oxygenation; ICU, intensive care unit.