Table 2.
Treatment | Number of rats | Ventral | Lateral | ||||||
---|---|---|---|---|---|---|---|---|---|
Incidence of carcinoma | % of lesions in prostate | Incidence of carcinoma | % of lesions in prostate | ||||||
LG‐PIN | HG‐PIN | Carcinoma | LG‐PIN | HG‐PIN | Carcinoma | ||||
Control | 11 | 11 (100%) | 6.6 ± 2.5 | 81.8 ± 4.8 | 11.7 ± 4.5 | 10 (91%) | 11.8 ± 5.2 | 82.8 ± 6.8 | 5.4 ± 3.9 |
100 mg/L | 11 | 11 (100%) | 8.0 ± 2.5 | 83.6 ± 3.8 | 8.4 ± 2.8* | 10 (91%) | 17.4 ± 4.3 | 80.1 ± 4.3 | 2.5 ± 1.4* |
500 mg/L | 11 | 11 (100%) | 8.3 ± 1.6 | 87.3 ± 3.2** | 4.4 ± 1.9*** | 6 (55%) | 26.8 ± 9.9*** | 71.8 ± 9.0** | 1.5 ± 1.7** |
*,**,***Indicate significant difference from the control group, P < 0.05, 0.1, 0.001, respectively.