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. 2013 Nov 8;104(12):1705–1710. doi: 10.1111/cas.12297

Figure 3.

Figure 3

Antitumor effect of in vivo delivery of siRNAs targeting vasohibin‐2 (siVASH2) mixed with atelocollagen in an s.c. tumor model of ovarian cancer (DISS cells). Each siRNA was injected every 4 days and four times in total to s.c. tumors. Left, line graph showing the serial tumor growth of the two groups. Top right, photographs taken 18 days after initiation of siRNA treatment. Bottom right, column graph showing the expression of VASH2 mRNA in the DISS s.c. tumor determined using quantitative RT‐PCR. Data are presented as the mean and SDs (n = 4). Bar = 1 cm. *P < 0.05 versus negative control siRNA (Neg ctrl).