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. 2020 Nov 9;94(23):e01246-20. doi: 10.1128/JVI.01246-20

FIG 8.

FIG 8

Time course analysis of the in vitro ExoN activity of MERS-CoV nsp14. The ExoN activity of different recombinant nsp14 proteins (wt, D90A/E92A, E191D, and H229C) was evaluated by incubating 200 nM nsp14 and 800 nM nsp10 for 0, 5, 30, 60, and 90 min at 37°C. As controls, individual proteins (800 nM) were incubated for 90 min. For technical details, see the legend to Fig. 7.