Table 5.

Sensitivity and specificity of the IL‐5 production after stimulation with Ni and Pd calculated for the cut‐off level of 10 pg/mL IL‐5

IL‐5		Ni and Pd PT positive vs PT negative			Single Pd PT positive vs PT negative
Metal	Concentration	Sensitivity, %	Specificity, %	P value	Sensitivity, %	Specificity, %	P value
NiSO4	2.5 × 10−5M	90.00	90.	.011*	0.00	90.00	.999
NiSO4	1 × 10−5M	90.00	100	.0001***	0.00	100	.999
NiSO4	7.5 × 10−6M	90.00	100	.0001***	0.00	100	.999
PdCl2	1 × 10−3	0.00	100	.999	0.00	100	.999
PdCl2	5.0 × 10−4	10.00	100	.999	33.33	100	.2308
PdCl2	2.5 × 10−4	0.00	100	.999	33.33	100	.2308
PdCl2	1.25 × 10−4	50.00	100	.0325*	0.00	100	.999
PdCl2	6.25 × 10−4	50.00	100	.0325*	0.00	100	.999
PdCl2	3.13 × 10−5	50.00	100	.0325*	0.00	100	.999
PdCl2	1.56 × 10−5	40.00	100	.0867	0.00	100	.999
PdCl2	7.81 × 10−6	10.00	100	.999	0.00	100	.999
PdCl2	3.91 × 10−6	20.00	100	.4737	0.00	100	.999

Abbreviations: IL‐5, interleukin‐5; PT, patch test.

*p < .05, ***p < .0001