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. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: Clin Cancer Res. 2020 Mar 13;26(11):2556–2564. doi: 10.1158/1078-0432.CCR-19-3005

Figure 2.

Figure 2.

Serial dilution benchmarking of our MRD test for 100 and 500 mutations, versus digital droplet PCR for a single mutation, using 20ng admixtures of sheared genomic DNA from two well-characterized cell lines. A) Detection power for a range of tumor fractions using our MRD assay and an equivalent ddPCR single mutation assay. B) Fraction of replicate dilutions detected by our MRD assay and an equivalent ddPCR assay as well as the median detection power for those samples. C) Tumor fraction estimation benchmarking for several replicates across a range of tumor fractions.