LS mean IOP in the study eye by visit, timepoint, and treatment group (ITT population; LOCF). CI indicates confidence interval; IOP, intraocular pressure; ITT, intent-to-treat; LBN, latanoprostene bunod; LOCF, last observation carried forward; LS, least squares. *P<0.001. Figure 2 can be viewed in color online at www.glaucomajournal.com.