Table 2. Subtype-specific Sensitivity, Specificity and overall Accuracy across 15 test MB datasets.
| Study | Sample_Size | Group3_Sensitivity | Group3_Specificity | Group4_Sensitivity | Group4_Specificity | |
|---|---|---|---|---|---|---|
| EMTAB292 | 19 | 100% | 100% | 100% | 100% | |
| GSE10327 | 62 | 100% | 98% | 100% | 100% | |
| GSE12992 | 40 | 87.50% | 96.80% | 95% | 94.70% | |
| GSE21140 | 103 | 95.70% | 98.60% | 94.30% | 98.30% | |
| GSE30074 | 30 | 100% | 92.60% | 87.50% | 100% | |
| GSE37382 | 50 | 100% | 100% | 100% | 100% | |
| GSE41842 | 19 | 100% | 100% | 100% | 100% | |
| GSE49243 | 58 | NA | 100% | NA | 100% | |
| GSE50161 | 24 | 100% | 100% | 100% | 100% | |
| GSE50765 | 12 | NA | 100% | NA | 100% | |
| GSE62803 | 8 | 100% | 80% | 66.70% | 100% | |
| GSE67850 | 22 | 88.90% | 100% | 100% | 100% | |
| GSE73038 | 46 | 66.70% | 100% | 100% | 91.40% | |
| GSE74195 | 30 | 100% | 92.30% | 90.90% | 100% | |
| GSE85217 | 763 | 98.50% | 99.30% | 96.80% | 100% | |
| SHH_Sensitivity | SHH_Specificity | WNT_Sensitivity | WNT_Specificity | Accuracy | ||
| EMTAB292 | 100% | 100% | NA | 100% | 100% | |
| GSE10327 | 92.90% | 100% | 100% | 100% | 98.30% | |
| GSE12992 | 100% | 100% | 100% | 100% | 94.90% | |
| GSE21140 | 100% | 98.50% | 100% | 100% | 96.80% | |
| GSE30074 | 100% | 100% | 100% | 100% | 93.30% | |
| GSE37382 | 90% | 100% | NA | 97.80% | 97.80% | |
| GSE41842 | 100% | 100% | 100% | 100% | 100% | |
| GSE49243 | 98.30% | NA | NA | 98.30% | 98.30% | |
| GSE50161 | 100% | 100% | 100% | 100% | 100% | |
| GSE50765 | 100% | NA | NA | 100% | 100% | |
| GSE62803 | 100% | 100% | 100% | 100% | 85.71% | |
| GSE67850 | 100% | 94.10% | 100% | 100% | 95.50% | |
| GSE73038 | 100% | 100% | 100% | 100% | 93.30% | |
| GSE74195 | 100% | 100% | 100% | 100% | 95% | |
| GSE85217 | 100% | 98.50% | 100% | 100% | 98.40% | |