Table 2. Characteristics of renal case patients and controls (N = 54).
| ALL | Case | Control | p-value | ||||
|---|---|---|---|---|---|---|---|
| N* | N (%) | 18 (33.3%) | 36 (66.7%) | ||||
| Sex | |||||||
| Male | 54 | 49 (90.7%) | 14 (77.8%) | 35 (97.2%) | 0.038 | ||
| Female | 5 (9.3%) | 4 (22.2%) | 1 (2.8%) | ||||
| Age (years) | |||||||
| <25 | 54 | 17 (31.5%) | 7 (38.9%) | 10 (27.8%) | 0.733 | ||
| 25–29 | 13 (24.1%) | 5 (27.8%) | 8 (22.2%) | ||||
| 30–34 | 15 (27.8%) | 4 (22.2%) | 11 (30.6%) | ||||
| ≥35 | 9 (16.7%) | 2 (11.1%) | 7 (19.4%) | ||||
| Number of Years Working at Current Employer | |||||||
| = <2 | 51 | 10 (19.6%) | 5 (33.3%) | 5 (13.9%) | 0.184 | ||
| 3 to 6 | 18 (35.3%) | 6 (40%) | 12 (33.3%) | ||||
| 7 to 10 | 11 (21.6%) | 3 (20%) | 8 (22.2%) | ||||
| >10 | 12 (23.5%) | 1 (6.7%) | 11 (30.6%) | ||||
| Clinical Status at Enrollment | |||||||
| AKI Stage | |||||||
| AKIN Criteria not Met | 48 | 32 (66.7%) | 2 (11.1%) | 30 (100%) | <0.001 | ||
| Stage 1 | 5 (10.4%) | 5 (27.8%) | 0 (0%) | ||||
| Stage 2 | 7 (14.6%) | 7 (38.9%) | 0 (0%) | ||||
| Stage 3 | 4 (8.3%) | 4 (22.2%) | 0 (0%) | ||||
| Clinical Status at Baseline^ | |||||||
| Elevated Creatinine (>1.3 mg/dL male, >1.1 mg/dL female) | 48 | 0 (0%) | 0 (0%) | 0 (0%) | n/a | ||
| Hematocrit Anemia (<38.8% male, <34.9% female) | 31 | 1 (3.2%) | 0 (0%) | 1 (5.9%) | 1.000 | ||
| Mean SD (Range) or Median (Range) | |||||||
| Age (years) | 54 | 29 (19, 59) | 26.9 (20, 40) | 29.5 (19, 59) | 0.229 | ||
| Number of Years Working Current Employer | 54 | 4.7 (0.03, 35.9) | 3.6 (0.03, 18.0) | 6.6 (0.8, 35.9) | 0.226 | ||
| Changes from Baseline^ | |||||||
| Baseline Serum Creatinine (mg/dL) | 48 | 1.0 (0.7, 1.3) | 1.0 (0.7, 1.3) | 1.0 (0.8, 1.2) | 1.000 | ||
| Change (mg/dL) | 48 | 0.1 (-0.2, 3.3) | 1.2 (0.2, 3.3) | 0 (-0.2, 0.5) | <0.001 | ||
| Percent Change (%) | 48 | 10.0 (-22.2, 330.0) | 139.2 (16.7, 330.0) | 0 (-22.2, 62.5) | <0.001 | ||
| Ratio (Enrollment:Baseline) | 48 | 1.1 (0.8, 4.3) | 2.4 (1.2, 4.3) | 1.0 (0.8, 1.6) | <0.001 | ||
| Baseline Hematocrit (%) | 31 | 45 (38, 49) | 45.5 (39, 49) | 44 (38, 48) | 0.594 | ||
| Change (%) | 30 | -0.6 (-12, 8) | -9.0 (-12, -3.6) | 1.0 (-1, 8) | <0.001 | ||
| Percent Change (%) | 30 | -1.4 (-25.5, 19.5) | -20.5 (-25.5, -9.2) | 2.1 (-2.3, 19.5) | <0.001 | ||
| Ratio (Enrollment:Baseline) | 30 | 0.99 (0.75, 1.2) | 0.79 (0.75, 0.91) | 1.02 (0.98, 1.2) | <0.001 | ||
| Days Elapsed from Baseline | 48 | 180 (29, 361) | 92.5 (29, 188) | 255.5 (57, 361) | <0.001 | ||
| Baseline eGFR | 48 | 101.3 (69.0, 127.8) | 102.5 (69.0, 127.8) | 101.3 (75.7, 123.4) | 0.900 | ||
| Baseline Creatinine Clearance (mL/min) | 48 | 106.5 (70.8, 189.0) | 110.6 (70.8, 189.0) | 103.7 (88.6, 172.5) | 0.280 | ||
| Decrease from Baseline (mL/min) | 48 | 9.6 (-32.5, 113.4) | 57.9 (10.1, 113.4) | 0 (-32.5, 38.2) | <0.001 | ||
*Number of participants on whom data was available.
^Most recent laboratory data recorded within the prior year.