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. 2020 Nov 10;15(11):e0240988. doi: 10.1371/journal.pone.0240988

Table 5. Characteristics of subjects who developed CKD of unknown etiology.

  Case 1 Case 2
Sex Male Male
Age (years) 30.6 33.1
Month of Acute Presentation June 2016 April 2017
Occupation Seasonal sugarcane seed cutter; not working in the 1 month prior Seasonal sugarcane seed cutter; working in the 1 month prior
Healthy Baseline
    Creatinine (mg/dL) 1.2 1.3
    Hematocrit (%) Unknown* 42
    Hemoglobin (g/dL) Unknown* Unknown*
    Leukocytes (cells/mm3) Unknown* Unknown*
Acute Presentation
    Creatinine (mg/dL) 1.4 2.97
    Hematocrit (%) 32.0 31.3
    Hemoglobin (g/dL) Unknown* 10.4
    Leukocytes (cells/mm3) Unknown* 10400
    AKI Stage AKIN criteria not met 2
    Number of Days from Baseline to
        Acute Visit 30 97
    Number of Days from Acute to
        CKD Diagnosis 508 93
CKD Stage 3 3
Concentration of Trace Element in Toenail (mg/kg)
    Nickel 0.24 0.48
    Aluminum 62.64 30.47
    Vanadium 0.20 <MDL
    Manganese 1.63 1.36
    Iron 81.89 15.46
    Cobalt <MDL 0.02
    Copper 4.98 3.06
    Zinc 134.62 72.11
    Arsenic 0.11 <MDL
    Selenium 0.84 <MDL
    Cadmium <MDL <MDL
    Mercury 0.12 0.13
    Lead 0.06 <MDL
    Uranium <MDL <MDL
    Chromium 0.42 <MDL

*Reliance on retrospective review of medical records for clinical parameters resulted in unknown values for measurements not studied during clinical encounter.