Table 1.
Baseline characteristics of the patients.
| Group A (32) | Group B (43) | p | |
|---|---|---|---|
| Mean age in years (95% C.I.) | 67.5 (63–71) | 67.8 (64–71) | p = 0–65^ |
| Male Sex n (%) | 22 (69) | 30 (69) | p = 1.00* |
| Mean BMI (±SD) | 25.4 (3.74) | 25.03 (3.42) | p = 0.37^ |
| Oxygen support (on admission) | |||
| None n. (%) | 11 (34) | 16 (37) | p = 0.80* |
| Low flow oxygen (<10 l/min) | 6 (19) | 5 (11) | |
| High flow oxygen (>10 l/min) | 15 (47) | 22 (51) | |
| Coexisting conditions | |||
| Any condition n (%) | 15 (47) | 25 (58) | p = 0.33* |
| Hypertension | 15 (47) | 20 (46) | |
| Diabetes | 4 (13) | 8 (18) | |
| Others | 4 (9) | ||
| Chest CT n (%) | |||
| <50% lung involvement | 17 (53) | 20 (46) | p = 0.57* |
| >50% lung involvement | 15 (47) | 23 (53) | |
| Median laboratory values: | |||
| Oxygen saturation % (median and 95% C.I) | 91.7 (90–92) | 91.9 (91–92) | p = 0.29^^ |
| Creatinine mg/dL (median and 95% C.I.) | 1.2 (1.09–1.30) | 1.2 (1.0–1.43) | p = 0.75^^ |
| PCR mg/dL§ (median and 95% C.I.) | 14.2 (7.8–17.9) | 12.2 (10–15.1) | p = 0.90^^ |
| D–Dimer§§ ng/ml (median and 95% C.I.) | 1.3 (0.83–1.92) | 1.07 (0.70–1.70) | p = 0.65^^ |
| Total Lymphocyte count (x 103) | 0.9 (0.65–1–0) | 0.9 (0.7–1.1) | p = 0.77^^ |
| ISTH–SIC score** No (%) | |||
| 0 | 21 (66) | 26 (60) | (0 + 1 vs 2) p = 1.00* |
| 1 | 10 (31) | 14 (32) | |
| 2 | 1 (3) | 2 (5%) | |
| 3–4 | – | – | |
*Chi Square ^ Student t test ^^ Mann–Whitney rank-sum test §normal values <0.5 mg/dL §§normal values <0.4 ng/ml.
**International Society of Thrombosis and Haemostasis Sepsis Induced Coagulation Score [Iba et al. J Thromb Haemost. 2019; 17(11):1989–1994].