Figure 1.

Weight change (A) and percent total body weight loss (TBWL) (B) for each subject over 12 months following sleeve gastrectomy. Serum insulin levels in subjects with T2D (C) over 12 months post operatively. Comparison of HbA1C (%) levels in subjects with T2D (D) at three months to baseline. Dark blue dots indicate values measured at baseline (pre-operatively) and dark red dots indicate values measured during follow-up (post-operatively). Dashed lines between dots indicate missing data for a given subject. Data for each timepoint are summarized as means and 95% confidence intervals. In panel D, the two dark red horizontal lines indicate the HbA1C thresholds for defining prediabetes (bottom, dot-dashed, HbA1C = 5.7%) and diabetes (top, dashed, HbA1C = 6.5%). Significant differences adjusted for multiple testing were marked with the following thresholds: *P < 0.05; **P < 0.01, ***P < 0.001, ****P < 0.0001. T0, baseline; T3, 3 months post-op; T6, 6 months; T9, 9 months; T12, 12 months.