Figure 4.

Differential expression of 36,593 gene transcripts in whole blood from six subjects at three months following sleeve gastrectomy. The dashed horizontal line corresponds to a false discovery rate (FDR) of 5% (corresponding to nominal P = 0.0093). The dashed vertical line corresponds to a log₂ fold-change (FC) = 1.0. Transcripts showing significant and substantive differential expression (FDR < 5%, log₂ FC > 1.0) are plotted in red. All other transcripts not meeting these two criteria are plotted in light gray. Transcripts of interest are annotated with their respective gene names and are described in the main text (IL27, EGR1, SLCO2A1, IGF2, PDPK2P).