Figure 7.
Effects of U0126 treatment on gene expression. Cellular expression of markers of fibrogenesis (A) and genes encoding important ECM proteins (B) following 21-day treatment with CTGF or U0126 was determined by qPCR. Results were normalized to control samples maintained in MSCGM media. Reference targets used were a combination of GAPDH, TBP, and YWHAZ. Groups not connected by the same letter are significant (p < 0.05).