Table 1.

Inhibitory activities and binding affinities of the compounds towards different GH18 chitinases.

	μM
	SmChiB		OfChtI		HsCht		hAMCase
Compounds	Ki	Kd	Ki	Kd	Ki	Kd	Ki	Kd
Berberine	11.79	11.98	2333	20.61	1933	21.89	6533	58.03
4a	0.68	1.12	6.43	–	8.23	–	7.43	–
4b	2.36	2.99	7.28	–	11.39	–	4.62	–
4c	0.15	0.19	3.03	2.58	0.35	0.34	0.80	1.12