Table 1.

MRI settings.

	Volunteer					Patient
Region	Leg	Abdomen axial/ axial #2a	Abdomen coronal	Brain	Brain #2 (Peterson 2016)	Pancreatic cancer
Scanner	Aera (1.5 T, Siemens)	Avanto (1.5 T, Siemens)	Avanto (1.5 T, Siemens)	Avanto (1.5 T, Siemens)	Unknown	Ingenia (3T, Philips)
Orientation	Axial	Axial	Coronal	Axial	Axial	Axial
Resolution (mm2)	2.4  ×  2.4	2.7  ×  2.7	1.6  ×  1.6	2.3  ×  2.3	0.94  ×  0.94	3.0  ×  3.0
FOV (mm2)	188  ×  400	284  ×  350	400  ×  400	243  ×  300	240  ×  240	432  ×  108
Slice thickness (mm)	5.0	8.0	5.0	8.0	2.5	3.7
Slice gap (mm)	0.0	0.8	0.0	8.0	0.0	0.3
Slices	25	8	20	8	54	18
TR/TE (ms)	4800/58	1300b/113	5000/60	2900/113	Unknown	2200b/45
Respiratory compensation	—	Triggered (bellow)	None	—	—	Triggered (navigator)
b-values (s mm−2)	0, 10, 20, 25, 40, 50, 75, 100, 300, 500, 700, 900	0, 2, 7, 10, 20, 30, 40, 50, 65, 85, 110, 150, 250, 350, 450, (650, 900)a	0, 20, 40, 60, 120, 240, 480, 900	0, 2, 7, 10, 20, 30, 40, 50, 65, 85, 110, 150, 250, 350, 450, 650, 900	0, 10, 20, 30, 40, 60, 80, 100, 120, 140, 160, 180, 200, 300, 400, 500, 600, 700, 800, 900, 1000	0, 10, 20, 30, 40, 50, 75, 100, 150, 250, 400, 600
Directions	6	6	3	6	Trace image (3 directions)	15, 9, 9, 9, 9, 9, 4, 12, 4, 4, 16
Averages	b  <  75  →  1	1	5	1	Unknown	1
	b  ⩾  75  →  2
CPU time (s)		Axial/axial#2				Mean (range)
PCA-denoising	1.3	0.41/0.46	7.3	0.37	21.1	0.74 (0.67–0.86)
Mono-exponential	67.0	12.3/19.0	289.8	13.6	626.3	28.6 (24.5–33.8)
Bi-exponential	196.9	29.6/54.2	937.3	26.5	1355.2	80.8 (70.1–92.1)

^aBoth volunteers were scanned with the same protocol, except axial #2 included a 8 mm slice gap and b  =  650 and 900 s mm⁻².

^bTrue echo time depends on respiratory triggering. 1300 ms (volunteer) and 2200 ms (patient) were the minimum repetition times set.