Table 1. Clinicopathologic characteristics of patients in the ARHGEF11-low and ARHGEF11-high group.
| Patient Characteristics | ARHGEF11 low (N=166) | ARHGEF11 high (N=48) | P value |
| Age | 0.269 | ||
| Median (range) | 51 (18-79) | 46.5 (22-75) | |
| Gender | 0.399 | ||
| (Male/Female) | 140/26 | 38/10 | |
| HBV | 0.898 | ||
| (Positive / negative) | 143/23 | 41/7 | |
| Tumor size (cm) | 5.78±3.37 | 6.44±3.99 | 0.254 |
| AFP | 0.864 | ||
| ≤400 ng/mL | 98 | 29 | |
| >400 ng/mL | 68 | 19 | |
| AJCC-TNM stage | 0.244 | ||
| (I/II/III/IV) | 78/46/36/6 | 22/14/7/5 | |
| BCLC Classification | 0.012 | ||
| (0, A/B/C, D) | 125/35/6 | 40/3/5 | |
| Tumor number (Solitary/Multiple) | 129/37 | 43/5 | 0.054 |
| Cirrhosis (Yes/No) | 105/61 | 30/18 | 0.526 |
| ALT (U/L) | 46.60±43.15 | 38.31±40.28 | 0.424 |
| AST (U/L) | 47.51±36.70 | 39.82±38.78 | 0.934 |
HBV: hepatitis B virus; AFP: alpha fetoprotein; ALT: alanine aminotransferase; AST: aspartate aminotransferase; AJCC: American Joint Committee on Cancer; BCLC: Barcelona Clinic Liver Cancer