Table 1. Sex steroid plasma levels in intact animals under normal feeding and postnatal overfeeding conditions.
| Males | Females | |||||||
| Sex steroid (pg/ml) | NL-CD | SL-HFD | p-value | NL-CD | SL-HFD | p-value | ||
| Testosterone | 9347.12±2850.11 | 2070.24±421.49 | 0.027 | 80.49±19.95 | 122.16±36.97 | 0.323 | ||
| Dihydrotestosterone | 87.23±22.91 | 22.63±5.31 | 0.016 | 3.74±1.05 | 8.15±2.33 | 0.097 | ||
| Androstenedione | 669.91±169.78 | 133.64±20.40 | 0.007 | 47.47±2.94 | 73.38±14.72 | 0.089 | ||
| Estradiol | 0.32±0.32 | n.d. | n.a. | 3.19±0.13 | 8.46±2.33 | 0.032 | ||
| Progesterone | 909.23±125.72 | 765.00±317.08 | 0.679 | 18380.32±2037.92 | 16474.30±3361.90 | 0.626 | ||
| Estrone | n.d. | n.d. | n.a. | 1.00±0.27 | 2.79±1.68 | 0.278 | ||
NL-CD: normal litter, control diet. SL-HFD: small litter, high fat diet. Plasma was collected at PND-150 for determination of sex steroids by mass spectrometry. p-value: One-way ANOVA statistical analysis. n.d.: not detectable; n.a.: not available.