Table 4. Cell subsets and immunoglobulin detection for COVID-19 patients.
| Non-severe | Severe | |||||
| Age | <50 | 50~60 | 60~70 | ≥70 | Overall | (N=26) |
| N | (N=159) | (N=58) | (N=65) | (N=23) | (N=305) | (N=26) |
| Hemoglobin (g/L) | ||||||
| high | 46(28.9%) | 13(22.4%) | 1(1.5%) | 1(0%) | 61(20.0%) | 5(19.2%) |
| low | 6(3.8%) | 4(6.9%) | 7(10.8%) | 3(0%) | 20(6.6%) | 3(11.5%) |
| normal | 107(67.3%) | 41(70.7%) | 57(87.7%) | 19(100%) | 224(73.4%) | 18(69.2%) |
| RBC (×1012/L) | ||||||
| high | 42(26.4%) | 4(6.9%) | 1(1.5%) | 1(0%) | 48(15.7%) | 5(19.2%) |
| low | 5(3.1%) | 6(10.3%) | 11(16.9%) | 7(50.0%) | 29(9.5%) | 4(15.4%) |
| normal | 112(70.4%) | 48(82.8%) | 53(81.5%) | 15(50.0%) | 228(74.8%) | 17(65.4%) |
| WBC (×109/L) | ||||||
| high | 4(2.5%) | 0(0%) | 1(1.5%) | 0(0%) | 5(1.6%) | 5(19.2%) |
| low | 37(23.3%) | 14(24.1%) | 16(24.6%) | 9(0%) | 76(24.9%) | 7(26.9%) |
| normal | 118(74.2%) | 44(75.9%) | 48(73.8%) | 14(100%) | 224(73.4%) | 14(53.8%) |
| Basophil (×109/L) | ||||||
| normal | 159(100%) | 58(100%) | 65(100%) | 23(100%) | 305(100%) | 25(96.2%) |
| high | 0(0%) | 0(0%) | 0(0%) | 0(0%) | 0(0%) | 1(3.8%) |
| Basophil percentage (%) | ||||||
| normal | 159(100%) | 58(100%) | 65(100%) | 23(100%) | 305(100%) | 25(96.2%) |
| high | 0(0%) | 0(0%) | 0(0%) | 0(0%) | 0(0%) | 1(3.8%) |
| Eosinophil (×109/L) | ||||||
| low | 90(56.6%) | 37(63.8%) | 46(70.8%) | 19(50%) | 192(63.0%) | 23(88.5%) |
| normal | 69(43.4%) | 21(36.2%) | 19(29.2%) | 4(50%) | 113(37.0%) | 3(11.5%) |
| Eosinophil percentage (%) | ||||||
| low | 103(64.8%) | 41(70.7%) | 53(81.5%) | 19(50.0%) | 216(70.8%) | 23(88.5%) |
| normal | 56(35.2%) | 17(29.3%) | 12(18.5%) | 4(50.0%) | 89(29.2%) | 3(11.5%) |
| Lymphocyte (×109/L) | ||||||
| high | 1(0.6%) | 0(0%) | 0(0%) | 0(0%) | 1(0.3%) | 1(3.8%) |
| low | 27(17.0%) | 13(22.4%) | 18(27.7%) | 7(50.0%) | 65(21.3%) | 15(57.7%) |
| normal | 131(82.4%) | 45(77.6%) | 47(72.3%) | 16(50.0%) | 239(78.4%) | 10(38.5%) |
| Lymphocyte percentage (%) | ||||||
| high | 16(10.1%) | 2(3.4%) | 2(3.1%) | 0(0%) | 20(6.6%) | 1(3.8%) |
| low | 36(22.6%) | 18(31.0%) | 24(36.9%) | 9(50%) | 87(28.5%) | 19(73.1%) |
| normal | 107(67.3%) | 38(65.5%) | 39(60.0%) | 14(50%) | 198(64.9%) | 6(23.1%) |
| Monocyte (×109/L) | ||||||
| high | 8(5.0%) | 4(6.9%) | 3(4.6%) | 1(0%) | 16(5.2%) | 4(15.4%) |
| normal | 151(95.0%) | 54(93.1%) | 62(95.4%) | 22(100%) | 289(94.8%) | 22(84.6%) |
| Monocyte percentage (%) | ||||||
| high | 90(56.6%) | 37(63.8%) | 41(63.1%) | 17(100%) | 185(60.7%) | 8(30.8%) |
| low | 2(1.3%) | 0(0%) | 0(0%) | 0(0%) | 2(0.7%) | 4(15.4%) |
| normal | 67(42.1%) | 21(36.2%) | 24(36.9%) | 6(0%) | 118(38.7%) | 14(53.8%) |
| Neutrophil (×109/L) | ||||||
| high | 3(1.9%) | 0(0%) | 1(1.5%) | 0(0%) | 4(1.3%) | 4(15.4%) |
| low | 50(31.4%) | 15(25.9%) | 17(26.2%) | 7(0%) | 89(29.2%) | 5(19.2%) |
| normal | 106(66.7%) | 43(74.1%) | 47(72.3%) | 16(100%) | 212(69.5%) | 17(65.4%) |
| Neutrophil percentage (%) | ||||||
| high | 38(23.9%) | 21(36.2%) | 20(30.8%) | 11(50.0%) | 90(29.5%) | 19(73.1%) |
| low | 22(13.8%) | 6(10.3%) | 2(3.1%) | 2(0%) | 32(10.5%) | 1(3.8%) |
| normal | 99(62.3%) | 31(53.4%) | 43(66.2%) | 10(50.0%) | 183(60.0%) | 6(23.1%) |
| CD45 count (cell/μl) | ||||||
| high | 1(0.6%) | 1(1.7%) | 1(1.5%) | 0(0%) | 3(1.0%) | 0(0%) |
| low | 18(11.3%) | 11(19.0%) | 13(20.0%) | 7(50.0%) | 49(16.1%) | 15(57.7%) |
| N | 2(1.3%) | 0(0%) | 0(0%) | 0(0%) | 2(0.7%) | 0(0%) |
| normal | 138(86.8%) | 46(79.3%) | 51(78.5%) | 15(50.0%) | 251(82.3%) | 11(42.3%) |
| CD3 count (cell/μl) | ||||||
| high | 3(1.9%) | 1(1.7%) | 1(1.5%) | 0(0%) | 5(1.6%) | 0(0%) |
| low | 22(13.8%) | 16(27.6%) | 19(29.2%) | 10(50.0%) | 68(22.3%) | 18(69.2%) |
| N | 2(1.3%) | 0(0%) | 0(0%) | 0(0%) | 2(0.7%) | 0(0%) |
| normal | 132(83.0%) | 41(70.7%) | 45(69.2%) | 11(50.0%) | 230(75.4%) | 8(30.8%) |
| CD3 percentage (%) | ||||||
| high | 6(3.8%) | 2(3.4%) | 2(3.1%) | 0(0%) | 10(3.3%) | 0(0%) |
| low | 3(1.9%) | 2(3.4%) | 3(4.6%) | 1(0%) | 9(3.0%) | 6(23.1%) |
| N | 2(1.3%) | 0(0%) | 0(0%) | 0(0%) | 2(0.7%) | 0(0%) |
| normal | 148(93.1%) | 54(93.1%) | 60(92.3%) | 20(100%) | 284(93.1%) | 20(76.9%) |
| CD4 percentage (%) | ||||||
| high | 1(0.6%) | 4(6.9%) | 1(1.5%) | 0(0%) | 6(2.0%) | 0(0%) |
| low | 14(8.8%) | 5(8.6%) | 8(12.3%) | 3(0%) | 30(9.8%) | 5(19.2%) |
| N | 2(1.3%) | 0(0%) | 0(0%) | 0(0%) | 2(0.7%) | 0(0%) |
| normal | 142(89.3%) | 49(84.5%) | 56(86.2%) | 20(100%) | 267(87.5%) | 21(80.8%) |
| CD8 count (cell/μl) | ||||||
| low | 9(5.7%) | 14(24.1%) | 17(26.2%) | 11(50%) | 51(16.7%) | 13(50.0%) |
| N | 2(1.3%) | 0(0%) | 0(0%) | 0(0%) | 2(0.7%) | 0(0%) |
| normal | 148(93.1%) | 44(75.9%) | 48(73.8%) | 12(50.0%) | 252(82.6%) | 13(50.0%) |
| CD8 percentage (%) | ||||||
| high | 4(2.5%) | 1(1.7%) | 1(1.5%) | 1(0%) | 7(2.3%) | 0(0%) |
| low | 1(0.6%) | 2(3.4%) | 7(10.8%) | 3(0%) | 13(4.3%) | 5(19.2) |
| N | 2(1.3%) | 0(0%) | 0(0%) | 0(0%) | 2(0.7%) | 0(0%) |
| normal | 152(95.6%) | 55(94.8%) | 57(87.7%) | 19(100%) | 283(92.8%) | 21(80.8%) |
| CD4/CD8 | ||||||
| high | 1(0.6%) | 6(10.3%) | 7(10.8%) | 3(0%) | 17(5.6%) | 2(7.7%) |
| low | 9(5.7%) | 1(1.7%) | 3(4.6%) | 1(0%) | 14(4.6%) | 1(3.8%) |
| N | 2(1.3%) | 0(0%) | 0(0%) | 0(0%) | 2(0.7%) | 0(0%) |
| normal | 147(92.5%) | 51(87.9%) | 55(84.6%) | 19(100%) | 272(89.2%) | 23(88.5%) |
| CD9 count (cell/μl) | ||||||
| high | 31(19.5%) | 6(10.3%) | 8(12.3%) | 0(0%) | 45(14.8%) | 1(3.8%) |
| low | 2(1.3%) | 1(1.7%) | 4(6.2%) | 5(50.0%) | 12(3.9%) | 9(34.6%) |
| N | 66(41.5%) | 17(29.3%) | 20(30.8%) | 6(50.0%) | 109(35.7%) | 1(3.8%) |
| normal | 60(37.7%) | 34(58.6%) | 33(50.8%) | 12(0%) | 139(45.6%) | 15(57.7%) |
| CD9 percentage (%) | ||||||
| high | 2(1.3%) | 2(3.4%) | 1(1.5%) | 3(0%) | 8(2.6%) | 5(19.2%) |
| low | 1(0.6%) | 0(0%) | 1(1.5%) | 4(0%) | 6(2.0%) | 2(7.7%) |
| N | 66(41.5%) | 17(29.3%) | 20(30.8%) | 6(50.0%) | 109(35.7%) | 1(3.8%) |
| normal | 90(56.6%) | 39(67.2%) | 43(66.2%) | 10(50.0%) | 182(59.7%) | 18(69.2%) |
| CD6CD56 count (cell/μl) | ||||||
| high | 4(2.5%) | 1(1.7%) | 4(6.2%) | 0(0%) | 9(3.0%) | 0(0%) |
| low | 11(6.9%) | 5(8.6%) | 5(7.7%) | 3(0%) | 24(7.9%) | 9(34.6%) |
| N | 66(41.5%) | 17(29.3%) | 20(30.8%) | 6(50.0%) | 109(35.7%) | 1(3.8%) |
| normal | 78(49.1%) | 35(60.3%) | 36(55.4%) | 14(50.0%) | 163(53.4%) | 16(61.5%) |
| CD6CD56 percentage (%) | ||||||
| high | 2(1.3%) | 0(0%) | 4(6.2%) | 1(0%) | 7(2.3%) | 3(11.5%) |
| low | 9(5.7%) | 1(1.7%) | 1(1.5%) | 2(0%) | 13(4.3%) | 0(0%) |
| N | 66(41.5%) | 17(29.3%) | 20(30.8%) | 6(50.0%) | 109(35.7%) | 1(3.8%) |
| normal | 82(51.6%) | 40(69.0%) | 40(61.5%) | 14(50.0%) | 176(57.7%) | 22(84.6%) |
| IgA (g/L) | ||||||
| high | 13(8.2%) | 9(15.5%) | 9(13.8%) | 0(0%) | 31(10.2%) | 4(15.4%) |
| N | 3(1.9%) | 2(3.4%) | 1(1.5%) | 0(0%) | 6(2.0%) | 0(0%) |
| normal | 143(89.9%) | 47(81.0%) | 55(84.6%) | 23(100%) | 268(87.9%) | 22(84.6%) |
| IgM (g/L) | ||||||
| high | 4(2.5%) | 1(1.7%) | 1(1.5%) | 0(0%) | 6(2.0%) | 1(3.8%) |
| low | 11(6.9%) | 10(17.2%) | 16(24.6%) | 10(50.0%) | 47(15.4%) | 3(11.5%) |
| N | 3(1.9%) | 2(3.4%) | 1(1.5%) | 0(0%) | 6(2.0%) | 0(0%) |
| normal | 141(88.7%) | 45(77.6%) | 47(72.3%) | 13(50%) | 246(80.7%) | 22(84.6%) |
RBC, red blood cell; WBC, white blood cell.