Table 1. Summary of included studies.
| Study | SNP | Risk allele/other allele | CAD | Country/ethnicity | No. of cases | No. of controls | Mean age (years) | Gender (M%) | |
| 1 | Schunkert (2011) | rs3825807 | A/G | C.A. & clinical verification | EU Ancestry | 45063 | 84589 | 51.03% | |
| 2 | Reilly (2011) | rs1994016 | C/T | C.A. | EU Ancestry | 12393 | 7383 | 54.7 | |
| Peden (2011) | rs4380028 | C/T | C.A. | EU Ancestry and South Asian | 36828 | 34247 | 59.3 | 52.40% | |
| 3 | Lu (2012) | rs1994016 | C/T | C.A. | China | 1010 | 3998 | 52.6 | 54.30% |
| rs3825807 | A/G | C.A. | |||||||
| rs4380028 | C/T | C.A. | |||||||
| 4 | Assimes (2016) | rs79265862 | G/A | C.A. | China | 3133 | 5423 | 65.5 | 59.05% |
| 5 | You (2016) | rs3825807 | A/G | C.A. | China | 4002 | 4152 | 60.3 | 66.20% |
| 6 | Chan (2017) | rs3825807 | A/G | C.A. | UK | 1076 | 283 | 62.5 | 70.10% |
| rs3825807 | A/G | C.A. | USA | 1710 | 974 | 63.8 | 68.70% | ||
| 7 | Matsunaga (2019) | rs28455815 | T/C | C.A. & clinical verification | Japan (BBJ-ToMMo, IMM, JPHC) | 12494 | 28879 | N/A | 51.80% |
| Japan (OACIS) | 2808 | 7261 | 63.5 | 63.50% | |||||
| UK Ancestry | 88192 | 162544 |
Abbreviations: BBJ, Biobank Japan; CA, coronary angiography; EU, European Union; IMM, Iwate Tohoku Medical Megabank Organization; JPHC, Japan Public Health Center-based Prospective; OACIS, Osaka Acute Coronary Insufficiency Study; SNP, single nucleotide polymorphism; ToMMo, Tohoku Medical Megabank Organization; UK, United Kingdom; USA, United States of America.