Table 3.
Overall agreement between assays (>50%).
| Reference | Comparison | N of comparison | TP | FN | FP | TN | Sensitivity | Specificity | Agreement | κ ∗ |
|---|---|---|---|---|---|---|---|---|---|---|
| Dako22C3 | SP142∗ | 115 | 8 | 8 | 2 | 97 | 50.0% | 98.0% | 91.3% | 0.569 |
| Dako28-8 | 107 | 8 | 3 | 6 | 90 | 72.7% | 93.8% | 91.6% | 0.593 | |
| SP142∗ | Dako22C3 | 115 | 8 | 2 | 8 | 97 | 80.0% | 92.4% | 91.3% | 0.569 |
| Dako28-8 | 109 | 7 | 2 | 7 | 94 | 77.8% | 93.1% | 91.8% | 0.565 | |
| Dako28-8 | Dako22C3 | 107 | 8 | 6 | 3 | 90 | 57.1% | 96.8% | 91.6% | 0.593 |
| SP142∗ | 109 | 7 | 7 | 2 | 94 | 50.0% | 97.9% | 91.8% | 0.565 |
TP: true positive; TN: true negative; FP: false positive; FN: false negative; TC: tumor cells; IC: immune cells. SP142 was scored by TC/IC > 50%/10%. ∗Cohen's kappa coefficient (κ).