Fig 1.

A 13-year-old girl with sickle cell disease. Pre-bone marrow transplantation axial DWI (A) (TR/TE = 10,000/83 ms, slice thickness = 5 mm) through the greater sphenoid wing (thin arrow) and occipital bone (thick arrow) and corresponding quantitative ADC map with ROIs (B) placed demonstrating reduced diffusion of the bone marrow. Follow-up MR imaging at 14 years of age from the same patient post-bone marrow transplantation with axial DWI (C) (TR/TE = 10,000/79.8 ms, slice thickness = 5 mm) at the same level as A and corresponding quantitative ADC map (D) demonstrating facilitated diffusion with respect to the pretransplantation scan.