Table 1:
Transplant group—hemoglobinopathy subtype, transplant data, and MR imaging data analyzeda
| Pt | Diagnosis | Source | Donor | HLA Match | Scans (No.) | Age (yr) | DWI (No.) | ASL (Right Cerebrum) (No.) | ASL (Left Cerebrum) (No.) |
|---|---|---|---|---|---|---|---|---|---|
| 1 | HbSS | BM | R | 8/8 | 2 | 18,19 | 2 | 2 | 2 |
| 2 | HbSS | BM | R | 8/8 | 4 | 15,16,16,18 | 4 | 4 | 4 |
| 3 | HbS-B0Th | PBSC | R, H | 4/8 | 2 | 12,13 | 2 | 2 | 2 |
| 4 | HbSC | BM | R | 8/8 | 5 | 13,14,14,16,17 | 5 | 5 | 5 |
| 5 | HbSS | BM | R | 8/8 | 4 | 7,10,11 | 3 | 3 | 3 |
| 6 | HbSS | BM | R | 8/8 | 2 | 7,9 | 2 | 2 | 2 |
| 7 | HbS-B0Th | BM | R | 8/8 | 2 | 10,12 | 2 | 2 | 2 |
| 8 | HbSS | BM | R | 8/8 | 3 | 11,11,12 | 3 | 2 | 2 |
| 9 | HbSS | BM | R | 8/8 | 4 | 5,7,8,9 | 4 | 4 | 4 |
| 10 | HbSS | UCB | R | 5/6 | 4 | 8,8,9,10 | 4 | 0 | 4 |
| 11 | HbSS | BM | R | 8/8 | 3 | 8,9,10 | 3 | 3 | 3 |
| 12 | HbSS | PBSC | R, H | 3/6 | 3 | 4,5,5 | 3 | 0 | 3 |
| 13 | HbSS | BM | U | 8/8 | 5 | 18,18,18,19,20 | 5 | 3 | 3 |
| 14 | HbSS | BM | R | 8/8 | 2 | 1,2 | 2 | 2 | 2 |
| 15 | HbSS | BM | R | 10/10 | 3 | 3,3,3 | 2 | 3 | 3 |
| 16 | HbSS | BM | R | 8/8 | 2 | 15,16 | 2 | 2 | 2 |
| 17 | HbSS | UCB | U | 6/6 | 3 | 3,3,4 | 3 | 3 | 3 |
Note:—Pt indicates patient; BM, bone marrow; PBSC, peripheral blood stem cell; UCB, umbilical cord blood; R, related; H, haploidentical; U, unrelated; HbSS, homozygous hemoglobin S; HbSC, sickle cell hemoglobin C; HbS-B0Th, hemoglobin S-β-thalassemia disease; HLA, human leukocyte antigen.
a
SCA subtype, transplant information, total MRI scans, number of DWIs, and number of ASL sequences analyzed (right and left cerebral hemispheres) from 17 patients with transplants.