Table 1:
Studies included in the meta-analysis
| Author | Year | No. of Patients, SRT/Asp | Mean Age (yr), SRT/Asp | Mean Baseline NIHSS, SRT/Asp | Mean Baseline ASPECTS, SRT/Asp | Anterior Circulation (%) | Study Design | Risk of Bias (NOS) |
|---|---|---|---|---|---|---|---|---|
| Delgado Almandoz et al17 | 2016 | 55/45 | 69.6/66.1 | 16.8/19.2 | 8.2/9.1 | 94% | Retrospective, single-center, case-control | 7 |
| Turk et al18 | 2015 | 30/64 | 62.5/68.5 | 17/16.5 | NA | 90% | Retrospective, single-center, case-control | 7 |
| Son et al29 | 2016 | 13/18 | 68.9/66.4 | 27.3/21.3 | NA | 0% | Retrospective, single-center, case-control | 6 |
| Kim et al20 | 2017 | 16/25 | 76.5/71 | 10.5/15 | 7/8 | 100% | Retrospective, single-center, case-control | 7 |
| Lapergue et al (a)19 | 2016 | 119/124 | 65.5/64.3 | 15.9/15.9 | 8/9 | 100% | Retrospective, multicenter, case-control | 7 |
| Mokin et al (a)16 | 2016 | 58/42 | NA | NA | NA | 0% | Retrospective, multicenter, case-control | 7 |
| Gerber et al22 | 2017 | 13/20 | 63.2/62.8 | 25/18 | 6.5/7.5 | 0% | Retrospective, single-center, case-control | 6 |
| Hentschel et al15 | 2017 | 67/69 | 66.2/66.1 | NA | NA | 90% | Retrospective, single-center, case-control | 7 |
| Hesse et al23 | 2018 | 286/164 | 74/72 | 15.5/15.3 | 8/8 | 100% | Retrospective, multicenter, case-control | 5 |
| Jadhav et al24 | 2017 | 195/112 | 69/66 | 17/17 | 9/9 | 87% | Retrospective, single-center, case-control | 6 |
| Lapergue et al (b)9 | 2017 | 189/192 | 68.1/71.7 | 16.1/16.3 | 7/7 | 100% | Randomized controlled trial, multicenter | 9 |
| Maegerlein et al25 | 2017 | 61/36 | 75.8/72.4 | NA | NA | 89% | Retrospective, multicenter, case-control | 5 |
| Mokin et al (b)21 | 2017 | 62/51 | NA | NA | NA | 100% | Retrospective, multicenter, case-control | 8 |
| Stapleton et al31 | 2018 | 70/47 | 69.4/63.5 | 16.5/16.5 | 8.3/8 | 100% | Retrospective, single-center, case-control | 7 |
| Gory et al26 | 2018 | 54/46 | 67/61 | 20/14 | 8/7 | 0% | Retrospective, multicenter, case-control | 7 |
| Mocco et al27 | 2018 | 136/133 | 71.1/71.8 | 7/6 | NA | 100% | Randomized controlled trial, multicenter | 9 |
| Nogueira et al28 | 2018 | 95/97 | 67.3/66.5 | 18/18 | 8/8 | 98% | Randomized controlled trial, multicenter | 9 |
| Nishi et al30 | 2018 | 45/44 | 73.1/77.8 | 19/17 | NA | 88% | Retrospective, single-center, case-control | 7 |
Note:—NOS indicates Newcastle-Ottawa Scale; NA, not available; Asp, aspiration.