Fig 1.

An overview of the AQ-PCMR image-processing pipeline and treatment flowchart of patients suspected of having CAH in this study. A, The phase-contrast MR imaging data acquired at the level of cerebral aqueduct are analyzed by Flow software to calculate the stroke volume and flow rate of each patient. B, One hundred eighty-five patients with gait abnormality and ventricular enlargement determined by the Evans index are included in this study. Depending on quantitative and subjective response to LP/LD, patients undergo shunt surgery. The shunt outcomes are determined within 12 months after surgery using both subjective assessment in 3 symptom categories and quantitative measurements such as the Tinetti, TUG, or MMSE scores.