Table 1:
Patient demographic and clinical characteristicsa
| Aggressive Tumor | Nonaggressive Tumor | P Value | |
|---|---|---|---|
| No. | 6 | 10 | |
| Volume change ratio | 14.4 ± 21.0 (−2.18–17.2) | 0.463 ± 1.135 (−1.40–3.78) | .003 |
| Doubling time (mo) | 5.77 ± 4.03 (0.73–10.8) | NA | |
| Age at first operation (yr) | 54.3 ± 9.9 | 45.8 ± 24.3 | .713 |
| Location of tumor (ratio of clival chordoma to all) | 3/6 | 8/10 | .299b |
| Postsurgical RT radiation dose (Gy) | 72.4 ± 33.5 (n = 4) | 74.2 ± 10.9 (n = 7) | .927 |
| Ratio of patients with postsurgical RT to all | 4/6 | 9/10 | .518b |
| Time from first operation to first follow-up MRI (mo) | 62.8 ± 53.3 | 71.4 ± 76.2 | >.99 |
| Time between the 2 follow-up MRIs (mo) | 9.1 ± 5.2 | 18.3 ± 12.5 | .022 |
| No. of surgical resections at first follow-up MRI | 2.00 ± 0.89 | 1.10 ± 0.32 | .056 |
| Sex (M/F) | 5:1 | 7:3 | >.99b |
| Histopathology (ratio of classic chordoma to all chordomas) | 6/6 | 5/10 | .093b |
| Mean ADC (×10−3 × mm2/s) | 1.055 ± 0.298 (0.78–1.37) | 1.622 ± 0.139 (1.34–1.65) | <.001 |
| Tumor volume (× 103 × mm3) | 21.2 ± 37.4 (0–60.4) | 3.44 ± 2.38 (0–7.46) | .492 |
Note:—NA indicates not applicable.
a
Numbers in the table represent mean ± SD. The numbers in parentheses indicate the 95% CIs.
b
P value was calculated by the Fisher exact test because the data were categoric.