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. 2020 Oct 27;8(10):e22108. doi: 10.2196/22108

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©Abhishek Pratap, Daniel Grant, Ashok Vegesna, Meghasyam Tummalacherla, Stanley Cohan, Chinmay Deshpande, Lara Mangravite, Larsson Omberg. Originally published in JMIR mHealth and uHealth (http://mhealth.jmir.org), 27.10.2020.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR mHealth and uHealth, is properly cited. The complete bibliographic information, a link to the original publication on http://mhealth.jmir.org/, as well as this copyright and license information must be included.

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Association between Neuro-QoL^TM domains and functional test performance in participants with MS. Neuro-QoL categories comprising <5% of total participants were not plotted. DSST (Digit Symbol Substitution Test): increase in DSST response time with increased severity in Neuro-QoL Cognition domain. Finger-tapping: increase in maximum finger tapping interval with increased severity in the Neuro-QoL Upper Extremity Function domain; Finger-to-nose: increase in hand rotation acceleration tremor feature with increased severity in Neuro-QoL Upper Extremity Function domain; MS: multiple sclerosis; Neuro-QoL: Quality of Life in Neurological Disorders; P0Y: maximum power in the inspected frequency interval of the Lomb–Scargle periodogram for the Y acceleration series (0.2–5 Hz); Walking: decrease in accelerometer-derived feature (P0Y) with increased severity in Neuro-QoL Lower Extremity Function domain.