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. 2019 May 29;44(6):757–769. doi: 10.1016/j.jgr.2019.05.009

Fig. 6.

Fig. 6

Expression of MVA pathway transcripts involved in saponin biosynthesis in P. quinquefolius and P. notoginseng. (A) Heatmap of gene expression in P. quinquefolius. (B) Heatmap of gene expression in P. notoginseng. AACT, acetoacetyl-CoA acyltransferase; DS, dammarenediol-II synthase; DXPR, 1-deoxy-o-xylulose 5-phosphate reductoisomerase; DXPS, 1-deoxy-o-xylulose 5-phosphate synthase; FPS, farnesyl pyrophosphate synthase; GDPS, geranyl diphosphatesynthase; HDS, 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphatesynthase; HMGS, 3-hydroxy-3-methylglutaryl-CoA synthase; HMGR, 3-hydroxy-3-methylglutaryl-CoA reductase; IPPI, isopentenyl pyrophosphate isomerase; ISPD, 2-C-methylerythritol 4-phosphatecytidyl transferase; ISPE, 4-(cytidine-5′-diphospho)-2-C-methylerythritol kinase; ISPH, 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase; MECPS, 2-C-methylerythritol-2,4-cyclophosphate synthase; MEP, methylerythritol phosphate; MVA, mevalonic acid; MVK, mevalonate kinase; MVD, mevalonate diphosphate decarboxylase; SE, squalene epoxidase; SS, squalene synthase. PVK, Phosphomevalonate kinase.