TABLE 5.
Functional data by genotype.
| rs41266431 | ||
| Genotype G/G | (A/G + A/A) | |
| (n = 21) | (n = 8) | |
| Median | ||
| Age (years) | 18 | 16 |
| Sex (m/f) (n) | (10/11) | (5/3) |
| P. aeruginosa+ (%) | 43% | 50% |
| FEV1 (% pred.) | 66 | 86.5 |
| FEF75 (% pred.) | 36.15 | 41 |
| VC (%predicted) | 74.33 | 84.5 |
| IL-8 pg/ml (Serum) | 12.4* | 6.7* |
| Leukocytes/μl (Sputum) | 2305# | 437.5# |
m, male; f, female; P. aeruginosa+, Pseudomonas aeruginosa colonization (intermittent + chronic); FEV1 (% predicted), forced expiratory volume in 1 s in% predicted, FEF75 (% predicted) maximum expiratory flow at 75% of forced vital capacity, VC(% predicted) vital capacity in% predicted *p < 0.052, #p < 0.025.