Table 4.
Gene ontology results from extremely upregulated 24 miRNAs (fold change cut off >2.0)
| Gene Set | Description | Enrichment ratio | p-value | FDR |
|---|---|---|---|---|
| Biological Processes (BP) | ||||
| GO:0007156 | Homophilic cell adhesion via plasma | 3.2174 | 1.1770e-8 | 0.000035666 |
| GO:0098742 | Cell-cell adhesion via plasma-membrane | 2.5358 | 1.1691e-7 | 0.00017713 |
| GO:0030099 | Myeloid cell differentiation | 2.1868 | 4.9157e-7 | 0.00044689 |
| GO:0031175 | Neuron projection development | 1.7059 | 4.3918e-7 | 0.00044689 |
| GO:0048666 | Neuron development | 1.6533 | 4.7477e-7 | 0.00044689 |
| GO:0048699 | Generation of neurons | 1.6481 | 3.8315e-9 | 0.000034832 |
| GO:0030182 | Neuron differentiation | 1.6467 | 2.6161e-8 | 0.000047566 |
| GO:0045944 | Positive regulation of transcription by RNA | 1.6351 | 2.6580e-7 | 0.00034519 |
| GO:0022008 | Neurogenesis | 1.6031 | 1.0945e-8 | 0.000035666 |
| GO:0006468 | Protein phosphorylation | 1.5305 | 1.9251e-8 | 0.000043753 |
| Cellular Components (CC) | ||||
| GO:0045202 | Synapse | 2.2821 | 0 | 0 |
| GO:0044456 | Synapse part | 2.1256 | 3.8531e- | 8.6364e-9 |
| GO:0030054 | Cell junction | 1.8931 | 1.8015e- | 3.0239e-8 |
| GO:0097458 | Neuron part | 1.8893 | 1.0347e- | 6.0790e-11 |
| GO:0043005 | Neuron projection | 1.8638 | 4.3436e- | 6.3796e-8 |
| GO:0098805 | Whole membrane | 1.8445 | 3.5398e- | 1.3864e-9 |
| GO:0005887 | Integral component of plasma membrane | 1.8253 | 1.6646e- | 4.8899e-9 |
| GO:0031226 | Intrinsic component of plasma membrane | 1.7831 | 4.4101e- | 8.6364e-9 |
| GO:0044463 | Cell projection part | 1.7663 | 3.2440e-9 | 3.8118e-7 |
| GO:0120038 | Plasma membrane bounded cell projection | 1.7663 | 3.2440e-9 | 3.8118e-7 |
| Molecular Functions (MF) | ||||
| GO:0001012 | RNA polymerase II regulatory region | 1.9494 | 2.4542e- | 0.0000094567 |
| GO:0000977 | RNA polymerase II regulatory region | 1.9123 | 8.2815e- | 0.000022206 |
| GO:0016773 | Phosphotransferase activity, alcohol | 1.9041 | 3.4398e- | 0.000010761 |
| GO:0044212 | Transcription regulatory region DNA | 1.8801 | 7.5765e- | 0.0000068572 |
| GO:0001067 | Regulatory region nucleic acid binding | 1.8759 | 8.4200e- | 0.0000068572 |
| GO:0000976 | Transcription regulatory region sequence- | 1.8594 | 1.3786e- | 0.000028751 |
| GO:1990837 | Sequence-specific double-stranded DNA | 1.8351 | 1.3181e- | 0.000028751 |
| GO:0003690 | Double-stranded DNA binding | 1.7775 | 1.6863e- | 0.000031653 |
| GO:0000981 | DNA-binding transcription factor activity, | 1.6004 | 2.5191e- | 0.0000094567 |
| GO:0003700 | RNA -binding transcription factor activity | 1.5945 | 1.0960e- | 0.0000068572 |