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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Neurobiol Learn Mem. 2020 Sep 20;175:107314. doi: 10.1016/j.nlm.2020.107314

Figure 1.

Figure 1.

Experimental timeline and stimulation parameters. Within the dentate gyrus, an implanted local field potential and lactate-sensitive biosensor were used to record evoked responses and extracellular [lac], respectively. Electrical stimulations of the medial perforant path were used to quantify synaptic strength, produce acute neuronal activation and associated changes in metabolic demand, and produce lasting synaptic potentiation within the dentate gyrus. At time points with two stimulation types, evoked response stimulation always preceded acute lactate stimulations.