Skip to main content
. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Neurobiol Learn Mem. 2020 Sep 20;175:107314. doi: 10.1016/j.nlm.2020.107314

Figure 3.

Figure 3.

High frequency stimulation (HFS) significantly potentiates the population spike of the evoked response for at least 72hrs. A) Typical input/output curve used to determine the baseline (BL) intensity of perforant path stimulation. BL intensity was chosen to produce an evoked response that contained a population spike equal to ~40% of the maximal population spike that could be elicited. Inset depicts a typical evoked response (SA: stimulation artifact, PS: population spike). B) Average evoked response observed during three separate stimulation periods in an individual rat (stimulation artifacts have been truncated to better visualize the evoked response). Grey arrow depicts time of stimulation. HFS was administered between BL and T0. C) Average population spike observed during each stimulation period (N = 9 rats; **p<0.01, *p<0.05 as compared to BL).