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. 2020 Oct 28;8:594090. doi: 10.3389/fcell.2020.594090

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Copyright © 2020 Ha, Kang, Lee, Baek, Kim, Chung, Lee and Kim.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Transcriptomic analysis of simBOs and 2D differentiation. (A) Heat map of differentially expressed genes between 2D and 3D differentiation. Expression value was normalized to those of iPSCs. Cluster name and gene number in each cluster were indicated in left panel and representative gene names in each cluster were indicated in the right panel. Color scale of expression value were presented in lower panel. (B) Bar chart for the –Log10(p.value) of representative enriched pathway calculated by reactome pathway enrichment analysis.