Table 1:
Comparative description of all study variables for adults with and without Down syndrome, 2013–2017 US Multiple Cause-of-Death Mortality files (N=13,332,871)
| Down syndrome (N=9,870) | No Down syndrome (N=13,323,001) | |
|---|---|---|
| Age - Mean(SD) | 55.51 (.10) | 74.09 (.00) |
| Female | 48.45% | 49.32% |
| Race-ethnicity | ||
| Non-Hispanic White | 82.47% | 78.91% |
| Non-Hispanic Black | 8.66% | 11.57% |
| Hispanic | 7.11% | 6.45% |
| Non-Hispanic Other | 1.75% | 3.07% |
| Year - Mean(SD) | 2015.07 (.01) | 2015.04 (.00) |
| Cause of death | ||
| Dementia/Alzheimer’s (ICD-10 codes F03, G30) | 20.70% | 8.17% |
| Diseases of the Heart (ICD-10 codes I00-I09, I11, I13, I20-I51) | 13.12% | 23.61% |
| Influenza and Pneumonia (ICD-10 codes J09-J18) | 11.85% | 2.07% |
| Pneumonitis due to solids and liquids (ICD-10 code J69) | 10.00% | 0.73% |
| CVA - Cerebrovascular Diseases (ICD-10 codes I60-I69) | 3.01% | 5.18% |
| Respiratory failure, not elsewhere classified (ICD-10 code J96) | 2.40% | 0.35% |
| Genitourinary diseases - Nephritis, nephrotic syndrome and nephrosis, urinary tract infection (ICD-10 codes N00-N07, N17-N19, N25-N27, N39) | 2.38% | 2.29% |
| Choking - Aspiration, ingestion, or inhalation of gastric contents, food, or other objects (ICD-10 codes W78-W80) | 2.21% | 0.19% |
| Congenital Heart Defect (ICD-10 codes Q20-Q28) | 2.14% | 0.05% |
| Malignant Neoplasms (ICD-10 codes C00-C97) | 2.05% | 22.26% |
| Unknown/unspecified (No ICD-10 code, R-codes) | 9.02% | 1.16% |