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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: Cell Immunol. 2020 Sep 16;358:104216. doi: 10.1016/j.cellimm.2020.104216

Figure 5. Evaluation of FVIII gene expression levels and anti-FVIII inhibitor antibody titers following adoptive transfer of F8CAR-Tregs in HemA mice.

Figure 5.

Mouse experiments were the same as those described in Figure 4. Plasma samples were separated from retro-orbitally collected blood. (A) A FVIII-specific aPTT assay was used to examine FVIII activity over time. Data are expressed as mean with standard deviation. (B) Bethesda assays were used to evaluate the anti-FVIII inhibitory antibody titers in the plasma at 9 weeks post adoptive transfer of F8CAR-Tregs. Data shown were expressed as a mean with standard deviation. *p < 0.05.