Table 2.
Tumors with Somatic BAP1 Mutations | |||||
---|---|---|---|---|---|
Tumor Type | Total no. of tumors, N | N | % | Comments | Ref. |
Uveal melanoma | 142 | 43 | 30% | [37] | |
31 | 26 | 84% | Metastatic uveal melanoma | [38] | |
Malignant mesothelioma | 42 | 20 | 48% | Most common mutation in malignant mesothelioma; BAP1 alterations are more common in pleural than in peritoneal mesotheliomas | [40] |
22 | 14 | 64% | [39] | ||
Renal cell carcinoma | 445 | 39 | 9% | [42] | |
Cutaneous melanoma | 60 | 3 | 5% | [31] |