Table 2.
Comparison of hematologic parameters by race/ethnicity.
| NHW | NHB | Hispanic | NHO | P value | |
|---|---|---|---|---|---|
| AL amyloidosis type, n (%) | |||||
| AL alone | 1862 (90%) | 171 (89%) | 76 (87%) | 55 (93%) | |
| MM-associated AL | 154 (7%) | 20 (10%) | 10 (12%) | 3 (5%) | |
| Othera | 62 (3.0%) | 1 (<1%) | 1 (1%) | 1 (2%) | 0.155 |
| Involved light chain (N = 2280), n (%) | |||||
| κ | 456 (23%) | 39 (21%) | 20 (24%) | 13 (22%) | |
| λ | 1492 (77%) | 150 (79%) | 65 (76%) | 45 (78%) | 0.857 |
| dFLCb (N = 1640) | |||||
| Median, mg/L (IQR) | 89 (27–269) | 116 (23–310) | 76 (24–168) | 90 (29–177) | 0.416 |
| ≥180 mg/L, n (%) | 455 (33%) | 54 (39%) | 16 (24%) | 11 (22%) | 0.044 |
MM multiple myeloma, dFLC difference between involved and uninvolved free light chains, IQR interquartile range.
aOther types included Waldenström macroglobulinemia-associated or lymphoplasmacytic lymphoma-associated AL amyloidosis.
bThe serum free light-chain assay was unavailable before 2003.