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. 2020 Nov 10;10(11):118. doi: 10.1038/s41408-020-00385-0

Table 4.

Multivariable Cox proportional hazard ratios for all-cause mortality with stepwise adjustments for patient characteristics.

Median OS (years) Unadjusted Model 1 Model 2 Model 3 Model 4
HR (95% CI) P value HR (95% CI) P value HR (95% CI) P value HR (95% CI) P value HR (95% CI) P value
NHW 3.4 Ref. Ref. Ref. Ref. Ref.
NHB 2.5 1.15 (0.95–1.37) 0.145 1.24 (1.03–1.49) 0.020 1.19 (0.93–1.50) 0.161 0.92 (0.63–1.35) 0.673 0.82 (0.50–1.34) 0.427
Hispanic 4 0.92 (0.70–1.22) 0.573 0.97 (0.73–1.29) 0.846 1.05 (0.72–1.52) 0.811 0.93 (0.57–1.52) 0.082 0.60 (0.29–1.23) 0.162
NHO 7.9 0.61 (0.39–0.95) 0.029 0.72 (0.46–1.13) 0.151 0.61 (0.36–1.04) 0.069 0.61 (0.29–1.32) 0.210 0.70 (0.32–1.52) 0.367
Overall P among groups 0.059 0.050 0.133 0.631 0.377

Model 1 adjusted for demographic variables only (age, sex). Model 2 added sociodemographic and lifestyle variables (education, marital status, smoking, alcohol consumption, BMI). Model 3 added physiologic variables (BU cardiac stage, dFLC >180 mg/mL). Model 4 added stem cell transplantation treatment. The overall P value derived by Type III test estimated the effect of race/ethnicity in each model.

OS overall survival, HR hazard ratio, CI confidence interval, ref. reference group.

Bold values signify statistical significance.