Table 3.
Correlation between the relative DPP4 mRNA expression levels, biochemical indices, and the NAFLD activity score.
| N = 29 | Liver DPP4 mRNA | |
|---|---|---|
| r | p-value | |
| Body weight (g) | 0.51 | < 0.01 |
| Liver weight (g) | 0.57 | < 0.01 |
| Liver to body weight (%) | 0.57 | < 0.01 |
| NAFLD activity score | 0.55 | < 0.01 |
| Hepatic triglyceride (mg/g) | 0.64 | < 0.01 |
| Fasting serum glucose (mg/dL) | 0.16 | 0.42 |
| Fasting serum insulin (ng/dL) | 0.08 | 0.67 |
| Serum total cholesterol (mg/dL) | 0.56 | < 0.01 |
| Serum free fatty acids (mM) | 0.40 | 0.05 |
| Serum AST (IU/L) | 0.70 | < 0.01 |
| Serum ALT (IU/L) | 0.63 | < 0.01 |
| TRAIL-R2 mRNA | 0.63 | < 0.01 |
Data are presented as Spearman’s rank correlation coefficient (r). p < 0.05 was regarded as statistically significant.
ALT, alanine aminotransferase; AST, aspartate aminotransferase; DPP4, dipeptidyl peptidase-4; NAFLD, non-alcoholic fatty liver disease; TRAIL-R2, TNF-related apoptosis-inducing ligand receptor 2.