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. 2020 Oct 28;10:595466. doi: 10.3389/fonc.2020.595466

Figure 4.

Figure 4

Effects of radiotherapy and DHA on apoptosis-related signaling pathways in A549 and A549/X cells. (A) The expressions of TRIM21, apoptosis-related proteins Bcl-2, cleaved caspases-3, cleaved caspases-8, Bim, and EMT-related proteins Vimentin, E-Cadherin, Snail, and N-Cadherin in A549 and A549/X cell lines treated with vehicle, D, R, D+R by western blot. The values are expressed as means ± SEM. ap < 0.05 vs. the A549 group, bp < 0.05 vs. the A549/X group, cp < 0.05 vs. the A549/X-R group. (B) The expressions of TRIM21, apoptosis-related proteins Bcl-2, cleaved caspases-3, cleaved caspases-8, Bim, and EMT-related proteins Vimentin, E-Cadherin, Snail, and N-Cadherin in A549/X, A549/X-NC, and A549/X-Si-PD-L1 treated with vehicle, D, R, D+R by western blot. The values are expressed as means ± SEM. ap < 0.05 vs. the A549/X-NC group, bp < 0.05 vs. the A549/X-Si-PD-L1 group, cp < 0.05 vs. the A549/X-Si-PD-L1+R group.