TABLE 3.

Proportion of variance in liability to internalizing phenotypes from common and specific genetic and environmental risk factors in final independent pathway model (3ca) (95% confidence intervals)

	Additive genetic factors				Familial environmental factors		Unique environmental factors
Measure	A1	A2	As	Total	C1	Total	E1	E2	Es	Total
Anxiety	0.25 (0.03–0.48)	–	0.08 (0.04–0.13)	0.33	0.25 (0.06–0.44)	0.25	0.25 (0.17–0.34)	0.02 (<0.01–0.04)	0.16 (0.12–0.21)	0.43
Anxiety sensitivity	0.18 (0.01–0.41)	–	–	0.18	0.26 (0.08–0.41)	0.26	0.31 (0.21–0.41)	–	0.25 (0.21–0.30)	0.56
Behavioral Inhibition	0.29 (0.08–0.45)	–	0.07 (0.01–0.14)	0.34	0.07 (<0.01–0.22)	0.07	0.34 (0.23–0.47)	–	0.22 (0.16–0.29)	0.56
Fear	0.11 (<0.01–0.32)	–	0.06 (<0.01–0.13)	0.17	0.23 (0.09–0.36)	0.23	0.28 (0.18–0.39)	–	0.31 (0.25–0.39)	0.59
Neuroticism	0.53 (0.32–0.64)	–	–	0.53	0.03 (<0.01–0.21)	0.03	0.17 (0.10–0.29)	0.14 (0.08–0.22)	0.12 (0.08–0.16)	0.43
Depression	0.30 (0.10–0.46)	–	0.12 (0.05–0.19)	0.42	0.11 (0.01–0.28)	0.11	0.05 (0.01–0.11)	0.17 (0.10–0.26)	0.24 (0.17–0.32)	0.46
Irritability	0.22 (0.10–0.35)	–	0.08 (<0.01–0.18)	0.30	0.02 (<0.01–0.12)	0.02	0.06 (0.01–0.13)	0.18 (0.09–0.29)	0.44 (0.33–0.55)	0.68
Behavioral activation	0.04 (0.01–0.11)	0.44 (0.34–0.54)	–	0.48	0.03 (<0.01–0.11)	0.03	0.08 (0.04–0.15)	–	0.40 (0.31–0.50)	0.47
Extraversion	–	0.56 (0.45–0.69)	0.15 (0.01–0.26)	0.71	0.004 (<0.01–0.03)	0.004	–	0.03 (0.01–0.06)	0.27 (0.21–0.33)	0.30

Note: A1, A2, and As—common and specific additive genetic factors; C1 and Cs—common and specific familial environmental factors; E1, E2, and Es—common and specific unique environmental factors. Bolded columns designate proportion of total variance accounted for by the combined common and specific etiological sources of variance for each measure. Total columns may not add up to 1.00 across factors due to rounding error.