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. 2020 Oct 29;20(6):388. doi: 10.3892/ol.2020.12251

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Copyright: © Du et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Circ_0008450 regulated the viability, apoptosis and glycolysis of hepatocellular cancer cells via miR-431 following hypoxia treatment. (A) Influence of miR-431 repression on circ_0008450 downregulation-mediated miR-431 expression was analyzed by reverse transcription-quantitative PCR. Effect of miR-431 inhibition on circ_0008450 reduction-mediated (B) viability, (C) apoptosis, (D and E) glycolysis in hypoxia-treated SNU-387 and Huh7 cells were determined using Cell Counting kit-8, flow cytometry and glycolysis assays. *P<0.05. circ, circular; miR, microRNA; si-, small interfering; H, hypoxic; N, normoxic; NC, negative control.